Bosses
Most regions have a mini-boss on stage 4 and a boss on stage 7; Spire Hill Crypt ends with its mini-boss and Spire Hill Crypt Lower with a boss on stage 3. Entering a boss stage needs a skull of the difficulty played, used up when the stage is cleared. The final boss is Lord of the Cinder on The Cinder Crown: 7.
Bosses and mini-bosses
Bloodmoon WerewolfKings Woods · level 10 · base health 900
OgreSpire Hill Crypt Lower · level 19 · base health 4,000
Ancient Oak TreantKings Woods South · level 28 · base health 6,000
Dread Sand ManticoreTazan Wastes · level 34 · base health 6,000
Dreamwood Treasure DrakeDream realms · level 30 · base health 300
Tidewrath Crab KingTazan Isles · level 40 · base health 6,000
Redrock LordThe Barrens · level 46 · base health 6,000
Lord of the Crimson ValeThe Crimson Vale · level 52 · base health 6,500
Dreamsand Treasure DrakeDream realms · level 46 · base health 300
Frost DragonVeldak Highlands · level 58 · base health 7,000
Defiled WyrmThe Defiled Keep · level 64 · base health 6,000
Dreamvault Treasure DrakeDream realms · level 65 · base health 300
Lord of the CinderThe Cinder Crown · level 70 · base health 10,000
RaptorKings Woods · level 7 · base health 600
Dark Elf MageSpire Hill Crypt · level 16 · base health 900
Venom QueenKings Woods South · level 25 · base health 4,000
Sandstorm Harpy QueenTazan Wastes · level 32 · base health 3,200
Ancient ShellwardenTazan Isles · level 38 · base health 7,500
Serparmat the DevourerThe Barrens · level 44 · base health 3,000
Goblin GiantThe Crimson Vale · level 50 · base health 7,000
Ice HoundVeldak Highlands · level 56 · base health 5,700
Bone ReaperThe Defiled Keep · level 62 · base health 6,400
EmberfangThe Cinder Crown · level 68 · base health 6,000
Every mini-boss and the Tidewrath Crab King drop the skull of the difficulty played each time they are beaten (11 enemies; for online characters the game server plans the loot).
Enemy level 1-10 · 7 stages
Enemy level 11-16 · 4 stages
Enemy level 17-19 · 3 stages
Enemy level 20-28 · 7 stages
Enemy level 28-34 · 7 stages
Enemy level 34-40 · 7 stages
Enemy level 40-46 · 7 stages
Enemy level 46-52 · 7 stages
Enemy level 52-58 · 7 stages
Enemy level 58-64 · 7 stages
Enemy level 65-70 · 7 stages
Mythic Rift
All 20 region bosses and mini-bosses above are the boss pool of the Mythic Rift, where they fight at level 70 with tier-scaled health and damage.