Animals that are higher up the food chain generally absorb higher quantities of Stardust from their prey, and are therefore more likely to suffer negative effects.
The Eclipse Bear, for example, prepares for hibernation by consuming large amounts of food and accumulating fat stores. Unfortunately, this also means taking in a very large quantity of Stardust, which will eat away at the Eclipse Bear's flesh while it sleeps. Come spring, there will generally be very little of the animal left - maybe just a single ear or a few scraps of fur.
Because of this, Eclipse Bears generally have extremely short lifespans, and have become highly aggressive.